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Introduction

A total of 428 respiratory HAdV infections were studied from 1991 to 2007 in Korean children and the case fatality ratio was 5.1%

Hosts

Animals and humans [1]

Transmission / Exposure Route

Direct contact, fecal-oral transmission, and occasionally waterborne transmission [1]

Case Fatality Ratio

Case fatality ratios
Case Fatality Ratio Pathway/conditions Population References
48%(of over 300)   Immunocompromised [2]
5.1%(of 428)   1991-2007 Korean Children [3]

Incubation Period

3-10 days

Burden of Disease

Adenoviruses C in non-hospitalized Mexican children older than five years of age showed a rate of AdV infection of 23%. [4]

Duration of infectiousness and disease

Symptomology

Symptoms include colds, sore throat, bronchitis, pneumonia, diarrhea, pink eye, fever, bladder inflammation or infection, inflammation of stomach and and intestines, and neurologic disease. These symptoms can vary depending on how a person becomes infected. For example, breathing in adenovirus may be more likely to cause respiratory illnesses. [5]

Excretion Rates (see Exposure)

Adenovirus can persist in the tonsils, adenoids, and intestines for months or years. This is a persistent adenovirus infection which usually shows no symptoms. [5]

Immunity

Currently there is no vaccine available to the general public. However, military personnel can obtain a vaccine for adenovirus types 4 and 7. [5]

Microbiology

Medium-sized (90-100 nm), nonenveloped icosohedral viruses containing double-stranded DNA [5]

Enviromental Survival

Unusually stable to chemical and physical agents and to adverse pH conditions [1]

Dose Response Models

Route: inhalation, Response: infection

exponential

\[P(response)=1-exp(-k\times dose)\]

Optimized parameters:
k = 6.07E-01
ID50 = 1.14E+00

Data from Other Sources

Read more:

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by {{author}} On Global Water Pathogen Project

Classification:

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Other names:

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NCBI Publications on Risk Assesment:

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