Difference between revisions of "Salmonella meleagridis: Dose Response Models"
m |
m |
||
Line 6: | Line 6: | ||
==='''General overview of ''Salmonella'' and Salmonellosis'''=== | ==='''General overview of ''Salmonella'' and Salmonellosis'''=== | ||
− | ''Salmonella'' is a genus of rod-shaped, gram-negative, non-spore forming, predominantly motile enterobacteria, that cause more than 10<sup>4</sup> cases of infections per year in the United States. Salmonellosis is an important medical problem; although infection with non-typhoid ''Salmonella'' often causes mild self-limited illness, severe sequelae including death may occur, particularly in immunocompromised hosts. The incidence of salmonellosis is higher in developing than in developed countries and in developing countries, food handlers may be a reservoir for further transmission of infection | + | ''Salmonella'' is a genus of rod-shaped, gram-negative, non-spore forming, predominantly motile enterobacteria, that cause more than 10<sup>4</sup> cases of infections per year in the United States. Salmonellosis is an important medical problem; although infection with non-typhoid ''Salmonella'' often causes mild self-limited illness, severe sequelae including death may occur, particularly in immunocompromised hosts. The incidence of salmonellosis is higher in developing than in developed countries and in developing countries, food handlers may be a reservoir for further transmission of infection. ref name="Chalker and Blaser 1988"> |
+ | Chalker RB, Blaser MJ (1988) [http://www.jstor.org/stable/4454281 A review of human salmonellosis: III. Magnitude of Salmonella infection in the United States.] Reviews of Infectious Diseases 10(1): 111-124.</ref> | ||
Many species of ''Salmonella'' have been isolated from eggs and egg products. <ref name="McCullough and Eisele 1951,1">McCullough NB, Eisele CW (1951) Experimental Human Salmonellosis: III. Pathogenicity of Strains of Salmonella newport, Salmonella derby, and Salmonella bareilly Obtained from Spray-Dried Whole Egg. The Journal of Infectious Diseases 89(3): 209-213.</ref>. ''Salmonella enterica'' serotype Meleagridis is one of the most common serotypes of Salmonella. <ref name="Zaidi, McDermott et al. 2006">Zaidi MB, McDermott PF, et al. (2006) Nontyphoidal Salmonella from Human Clinical Cases, Asymptomatic Children, and Raw Retail Meats in Yucatan, Mexico. Clinical Infectious Diseases 42(1): 21-28.</ref>. Twenty human isolates of ''S. Meleagridis'' had been identified in Canada so far during 1997. | Many species of ''Salmonella'' have been isolated from eggs and egg products. <ref name="McCullough and Eisele 1951,1">McCullough NB, Eisele CW (1951) Experimental Human Salmonellosis: III. Pathogenicity of Strains of Salmonella newport, Salmonella derby, and Salmonella bareilly Obtained from Spray-Dried Whole Egg. The Journal of Infectious Diseases 89(3): 209-213.</ref>. ''Salmonella enterica'' serotype Meleagridis is one of the most common serotypes of Salmonella. <ref name="Zaidi, McDermott et al. 2006">Zaidi MB, McDermott PF, et al. (2006) Nontyphoidal Salmonella from Human Clinical Cases, Asymptomatic Children, and Raw Retail Meats in Yucatan, Mexico. Clinical Infectious Diseases 42(1): 21-28.</ref>. Twenty human isolates of ''S. Meleagridis'' had been identified in Canada so far during 1997. |
Revision as of 13:21, 18 September 2012
Contents
Salmonella enterica serotype Meleagridis
General overview of Salmonella and Salmonellosis
Salmonella is a genus of rod-shaped, gram-negative, non-spore forming, predominantly motile enterobacteria, that cause more than 104 cases of infections per year in the United States. Salmonellosis is an important medical problem; although infection with non-typhoid Salmonella often causes mild self-limited illness, severe sequelae including death may occur, particularly in immunocompromised hosts. The incidence of salmonellosis is higher in developing than in developed countries and in developing countries, food handlers may be a reservoir for further transmission of infection. ref name="Chalker and Blaser 1988"> Chalker RB, Blaser MJ (1988) A review of human salmonellosis: III. Magnitude of Salmonella infection in the United States. Reviews of Infectious Diseases 10(1): 111-124.</ref>
Many species of Salmonella have been isolated from eggs and egg products. [1]. Salmonella enterica serotype Meleagridis is one of the most common serotypes of Salmonella. [2]. Twenty human isolates of S. Meleagridis had been identified in Canada so far during 1997.
Summary Data
McCullough, and Eisele (1951) inoculated human volunteers orally with the S. Meleagridis strain I,II and III.[3]
|
Optimization Output for experiment 238
|
|
|
Optimization Output for experiment 240
|
|
|
Summary
The data set of Salmonella Meleagridis strain II failed to show test of trend and hence was not analyzed. Strain II and strain III could not be pooled.
References
- ↑ McCullough NB, Eisele CW (1951) Experimental Human Salmonellosis: III. Pathogenicity of Strains of Salmonella newport, Salmonella derby, and Salmonella bareilly Obtained from Spray-Dried Whole Egg. The Journal of Infectious Diseases 89(3): 209-213.
- ↑ Zaidi MB, McDermott PF, et al. (2006) Nontyphoidal Salmonella from Human Clinical Cases, Asymptomatic Children, and Raw Retail Meats in Yucatan, Mexico. Clinical Infectious Diseases 42(1): 21-28.
- ↑ 3.0 3.1 3.2 3.3 3.4 McCullough NB, Eisele CW (1951) Experimental human salmonellosis. II. Immunity studies following experimental illness with Salmonella meleagridis and Salmonella anatum. Journal of immunology (Baltimore, Md. : 1950) 66(5): 595-608.