Difference between revisions of "SARS coronavirus"
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=='''''SARS coronavirus''''' (Severe Acute Respiratory Syndrome)== | =='''''SARS coronavirus''''' (Severe Acute Respiratory Syndrome)== | ||
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===Hosts=== | ===Hosts=== | ||
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===Transmission/Exposure Routes=== | ===Transmission/Exposure Routes=== | ||
| − | Primarily via close person-to-person contact, through droplet transmission | + | Primarily via close person-to-person contact, through droplet transmission <ref name=Medscape>[http://emedicine.medscape.com/article/237755-overview#showall Medscape]</ref> |
===Incubation Times=== | ===Incubation Times=== | ||
| − | Maximum is 10 days | + | Maximum is 10 days <ref name=Update>Update 49 - SARS case fatality ratio, incubation period, World Health Organization, 7 May 2003. URL Accessed 17 May 2008. [http://www.who.int/csr/sarsarchive/2003_05_07a/en/# Full text]</ref> |
===Case Fatality Ratios=== | ===Case Fatality Ratios=== | ||
| − | Less than 1% for people aged 24 or younger, 6% for those 25 to 44, 15% for those 45 to 64, and more than 50% for those over 65 | + | Less than 1% for people aged 24 or younger, 6% for those 25 to 44, 15% for those 45 to 64, and more than 50% for those over 65<ref name=Update></ref> |
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{| border = "1" | {| border = "1" | ||
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===Burden of Disease=== | ===Burden of Disease=== | ||
| − | In the 2002-2003 outbreak, more than 8,000 cases were identified, mostly in mainland China. North America saw 251 cases during that period | + | In the 2002-2003 outbreak, more than 8,000 cases were identified, mostly in mainland China. North America saw 251 cases during that period <ref name=Trivendi> |
| + | Trivendi, M. Pinsky, M. (2011) “Severe Acute Respiratory Syndrome (SARS)" Medscape Reference. Retrieved on 1-31-12 from http://emedicine.medscape.com/article/237755-overview#a0156</ref> | ||
====Duration of Infectiousness and disease==== | ====Duration of Infectiousness and disease==== | ||
====Symptomology==== | ====Symptomology==== | ||
| − | A high fever is typical (upwards of 38°C) at onset, after which headaches, general malaise, and diarrhea can occur. After 2 to 7 days, a dry cough may develop. Pneumonia is typical of most SARS patients. <ref> http://www.cdc.gov/sars/about/fs-SARS.html | + | A high fever is typical (upwards of 38°C) at onset, after which headaches, general malaise, and diarrhea can occur. After 2 to 7 days, a dry cough may develop. Pneumonia is typical of most SARS patients.<ref name=CDC>Center For Disease Control [http://www.cdc.gov/sars/about/fs-SARS.html Full Text]</ref> |
====Latency==== | ====Latency==== | ||
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===Microbiology=== | ===Microbiology=== | ||
| − | Coronaviruses are positive-strand, enveloped RNA viruses | + | Coronaviruses are positive-strand, enveloped RNA viruses <ref name=Wikipedia>[http://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome Wikipedia]</ref> |
===Recommended Dose Response Model=== | ===Recommended Dose Response Model=== | ||
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===References=== | ===References=== | ||
<references /> | <references /> | ||
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[[Category:PSDS]][[Category:Virus]] | [[Category:PSDS]][[Category:Virus]] | ||
Revision as of 20:57, 10 July 2012
Contents
Hosts
Humans
Transmission/Exposure Routes
Primarily via close person-to-person contact, through droplet transmission [1]
Incubation Times
Maximum is 10 days [2]
Case Fatality Ratios
Less than 1% for people aged 24 or younger, 6% for those 25 to 44, 15% for those 45 to 64, and more than 50% for those over 65[2]
| Age (Years) | Case Fatality Ratio |
| < 24 | < 1% |
| 25-44 | 6% |
| 45-64 | 15% |
| > 65 | > 50% |
Burden of Disease
In the 2002-2003 outbreak, more than 8,000 cases were identified, mostly in mainland China. North America saw 251 cases during that period [3]
Duration of Infectiousness and disease
Symptomology
A high fever is typical (upwards of 38°C) at onset, after which headaches, general malaise, and diarrhea can occur. After 2 to 7 days, a dry cough may develop. Pneumonia is typical of most SARS patients.[4]
Latency
Asymptomatic Rates
Excretion Rates (see Exposure)
Immunity
Microbiology
Coronaviruses are positive-strand, enveloped RNA viruses [5]
Recommended Dose Response Model
Dose response models for SARS
Exponential, k is 2.46E-03
References
- ↑ Medscape
- ↑ 2.0 2.1 Update 49 - SARS case fatality ratio, incubation period, World Health Organization, 7 May 2003. URL Accessed 17 May 2008. Full text
- ↑ Trivendi, M. Pinsky, M. (2011) “Severe Acute Respiratory Syndrome (SARS)" Medscape Reference. Retrieved on 1-31-12 from http://emedicine.medscape.com/article/237755-overview#a0156
- ↑ Center For Disease Control Full Text
- ↑ Wikipedia
