Rotavirus
Contents
Rotavirus
http://www.cdc.gov/rotavirus/index.html
Hosts
Animals and humans
Transmission/Exposure Routes
Fecal-oral and usually person-to-person but sometimes via contaminated water, food, or shellfish. Airborne respiratory transmission is possible (Wikipedia)
Incubation Times
1-3 days (CDC)
Case Fatality Ratios
Rotavirus was estimated to be the cause of 37 deaths annually when data were extrapolated to the US population (Fischer et al, 2007).
Burden of Disease
Rotavirus was estimated to be the cause of ~60,000 hospitalizations annually when data were extrapolated to the US population (Fischer et al, 2007).
Duration of Infectiousness and disease
Symptomology
Latency
Asymptomatic Rates
Excretion Rates (see Exposure)
Immunity
Microbiology
A genus of double-stranded RNA virus in the family Reoviridae
Environmental Resistance
Resistant to disinfection.
Recommended Dose Response Model
Dose response models for Rotavirus
Beta-Poisson, α is 2.53E-01, N50 is 6.17
References
http://en.wikipedia.org/wiki/Rotavirus
Thea Kølsen Fischer, Ce´ cile Viboud, Umesh Parashar, Mark Malek, Claudia Steiner, Roger Glass,and Lone Simonsen. (2007) Hospitalizations and Deaths from Diarrhea and Rotavirus among Children <5 Years of Age in the United States, 1993–2003. The Journal of Infectious Diseases. 195:1117–25 Full Text
http://www.cdc.gov/vaccines/pubs/surv-manual/chpt13-rotavirus.pdf