Rotavirus

Rotavirus

http://www.cdc.gov/rotavirus/index.html

Hosts

Animals and humans

Transmission/Exposure Routes

Fecal-oral and usually person-to-person but sometimes via contaminated water, food, or shellfish. Airborne respiratory transmission is possible (Wikipedia)

Incubation Times

1-3 days (CDC)

Case Fatality Ratios

Rotavirus was estimated to be the cause of 37 deaths annually when data were extrapolated to the US population (Fischer et al, 2007).

Burden of Disease

Rotavirus was estimated to be the cause of ~60,000 hospitalizations annually when data were extrapolated to the US population (Fischer et al, 2007).

Microbiology

A genus of double-stranded RNA virus in the family Reoviridae

Environmental Resistance

Resistant to disinfection.

Recommended Dose Response Model

Dose response models for Rotavirus
Beta-Poisson, α is 2.53E-01, N₅₀ is 6.17

References

http://en.wikipedia.org/wiki/Rotavirus
Thea Kølsen Fischer, Ce´ cile Viboud, Umesh Parashar, Mark Malek, Claudia Steiner, Roger Glass,and Lone Simonsen. (2007) Hospitalizations and Deaths from Diarrhea and Rotavirus among Children <5 Years of Age in the United States, 1993–2003. The Journal of Infectious Diseases. 195:1117–25 Full Text
http://www.cdc.gov/vaccines/pubs/surv-manual/chpt13-rotavirus.pdf