Difference between revisions of "Rotavirus"

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Revision as of 12:22, 3 August 2012

Rotavirus

Hosts

Animals and humans

Transmission/Exposure Routes

Fecal-oral and usually person-to-person but sometimes via contaminated water, food, or shellfish. Airborne respiratory transmission is possible.[1]

Incubation Times

1-3 days[2]

Case Fatality Ratios

Rotavirus was estimated to be the cause of 37 deaths annually when data were extrapolated to the US population [3]

Burden of Disease

Rotavirus was estimated to be the cause of ~60,000 hospitalizations annually when data were extrapolated to the US population.[3]

Duration of Infectiousness and disease

Symptomology

Symptoms of infected individuals include fever, vomiting, diarrhea, and abdominal pain. Loss of appetite and dehydration are also common, and especially harmful to infants and young children.[2]

Latency

Asymptomatic Rates

Excretion Rates (see Exposure)

Immunity

Microbiology

A genus of double-stranded RNA virus in the family Reoviridae

Environmental Resistance

Resistant to disinfection.

Recommended Dose Response Model


Dose response models for Rotavirus
Beta-Poisson, α is 2.53E-01, N50 is 6.17
Betapoisson model.jpg





References

http://www.cdc.gov/rotavirus/index.html

  1. http://en.wikipedia.org/wiki/Rotavirus
  2. 2.0 2.1 CDC
  3. 3.0 3.1 Thea Kølsen Fischer, Ce´ cile Viboud, Umesh Parashar, Mark Malek, Claudia Steiner, Roger Glass,and Lone Simonsen. (2007) Hospitalizations and Deaths from Diarrhea and Rotavirus among Children <5 Years of Age in the United States, 1993–2003. The Journal of Infectious Diseases. 195:1117–25 Full Text