Rhinovirus

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Rhinovirus

Hosts

Human

Transmission/Exposure Routes

Aerosols of respiratory droplets and from contaminated surfaces, including direct person-to-person contact [1]

Incubation Times

2-4 days [2]

Case Fatality Ratios

During a 6-week period in 2003 in a long term care facility for elderly persons, 56 residents and 26 staff developed respiratory illness in a long-term facility; 12 residents died.[3]

Burden of Disease

Fifty-two percent (615/1192) of patients from October 2009 to December 2009 had a single respiratory virus and 207 had rhinobirus. [4]


Duration of infectiousness and disease

Symptomology

Latency

Asymptomatic Rates

Excretion Rates (see Exposure)

Immunity

Microbiology

Small (30 nm), nonenveloped viruses that contain a single-strand RNA genome within an icosahedral (20-sided) capsid. Rhinoviruses belong to the Picornaviridae family.[5]

Environmental Survival


Recommended Dose Response Model

Dose response models for Rhinovirus
Beta-Poisson, α is 0.20 N50 is 9.22
Betapoisson model.jpg





References

  1. Wikipedia
  2. Justin Lessler, Nicholas G Reich, Ron Brookmeyer, Trish M Perl, Kenrad E Nelson, Derek A T Cummings. 2009. Incubation periods of acute respiratory viral infections: a systematic review. Lancet Infect Dis. 9: 291-300. Full Text
  3. Janice K. Louie, Shigeo Yagi, Fritzi A. Nelson, David Kiang, Carol A. Glaser, Jon Rosenberg, Christine K. Cahill, and David P. Schnurr. (2005) Rhinovirus Outbreak in a Long Term Care Facility for Elderly Persons Associated with Unusually High Mortality. CID. 41: 262-265 Full text
  4. Philip A. Chan, Leonard A. Mermel, Sarah B. Andrea, Russell McCulloh, John P. Mills, Ignacio Echenique, Emily Leveen, Natasha Rybak, Cheston Cunha, Jason T. Machan, Terrance T. Healey, and Kimberle C. Chapin. (2011) Distinguishing Characteristics between Pandemic 2009–2010 Influenza A (H1N1) and Other Viruses in Patients Hospitalized with Respiratory Illness. PLoS ONE. 6(9) Full text
  5. Medscape