PrP prion
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- Hosts
- Transmission/Exposure Routes
- Incubation Times
- Case Fatality Ratios
- Burden of Disease
- Microbiology
- Environmental Survival
- Recommended Dose Response Model
Human and animal [1]
Primary method of infection in animals is through ingestion[2]
Incubation periods of infection with human prions can exceed 50 years[3]
Prion-related diseases are relentlessly progressive and invariably lead to death. [2]
The most common prion disease is CJD, with a uniform incidence of approximately 1 case per million population both in the United States and internationally[2]
Duration of Infectiousness and disease
Symptomology
Latency
Asymptomatic Rates
Excretion Rates (see Exposure)
Immunity
An infectious agent composed of protein in a misfolded form