Escherichia coli

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Escherichia coli

Hosts

Animals and humans

Transmission/Exposure Routes

Fecal-oral route, and most illness has been associated with eating undercooked, contaminated ground beef, swimming in or drinking contaminated water, and eating contaminated vegetables; but direct person-to-person contact can also spread infection (www.azdhs.gov)

Case Fatality Ratios

Case fatality ratios
Case Fatality Ratio Pathway/conditions Population References
8% Neonatal Meningitis Not Reported (Medscape)
3-5% Developed hemolytic uremic syndrome Not Reported (www.azdhs.gov)
<1% Not Reported Overall (www.azdhs.gov)

Incubation Period

The incubation time for E. coli O157:H7 can be from 2 to 8 days, but it usually ranges from 3 to 4 days (www.azdhs.gov).

Burden of Disease

The incidence of E. coli O157:H7 and non-O157 infection per 100,000 population in 2008 is 1.12 and 0.45 (CDC MMWR).

Duration of infectiousness and disease

Symptomology

Severe stomach cramps, diarrhea, and vomiting are common symptoms of E. coli O157:H7 infections. Fever can occur but is usually less than 38.5˚C. Symptoms generally subside within 5-7 days, although more extreme cases do exist. [1]

Excretion Rates (see Exposure)

Immunity

Microbiology

Gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms (Wikipedia).

Environmental Survival

Recommended Dose Response Model

Dose response models for Escherichia coli
Beta-Poisson, α is 0.16, N50 is 2.11E+06
Betapoisson model.jpg


Dose response models for enterohemorrhagic Escherichia coli (EHEC)
Exponential, k is 2.18E-04
Exponential model.png





References

  1. http://www.cdc.gov/nczved/divisions/dfbmd/diseases/ecoli_o157h7/#symptoms CDC

http://en.wikipedia.org/wiki/Escherichia_coli
http://en.wikipedia.org/wiki/Escherichia_coli_O157:H7
http://emedicine.medscape.com/article/217485-overview#showall
http://www.azdhs.gov/phs/edc/edrp/pdf/escherichiacoliset.pdf
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5813a2.htm