Entamoeba coli

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Transmission/Exposure Routes

Fecal-oral, indirectly through contact with dirty hands or objects

Incubation Times

2 days to 4 months [1]

Case Fatality Ratios

Case fatality rates associated with amebic colitis range from 1.9%-9.1%. Amebic colitis evolves to fulminant necrotizing colitis or rupture in approximately 0.5% of cases; in such cases, the mortality rate jumps to greater than 40%. [2]
The mortality rate due to amebic liver abscess has fallen to 1-3% in the last century following the introduction of effective medical treatment. Nevertheless, amebic liver abscess is complicated by sudden intraperitoneal rupture in 2-7% of patients, leading to a higher mortality rate[3]

Burden of Disease

Asymptomatic intestinal amebiasis occurs in 90% of infected individuals. However, only 4%-10% of individuals with asymptomatic amebiasis who were monitored for one year eventually developed colitis or extraintestinal disease [4]
The overall prevalence of amebiasis is approximately 4% in the United States[1]
Entamoeba species infect approximately 10% of the world's population[1]

Duration of Infectiousness and disease



Asymptomatic Rates

Excretion Rates (see Exposure)



A non-pathogenic species of Entamoeba that frequently exists as a commensal parasite in the human gastrointestinal tract

Environmental Survival

Survive weeks to months in the external environment

Recommended Dose Response Model

Endamoeba coli: Dose Response Models
Beta-Poisson, α is 0.10, N50 is 340.78
Betapoisson model.jpg

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Medscape Pediatric Amebiasis

  1. 1.0 1.1 1.2 <Medscape
  2. Aristizábal H, Acevedo J, Botero M. Fulminant amebic colitis. World J Surg. Mar-Apr 1991;15(2):216-21 Full Text
  3. Stanley SL Jr. Amoebiasis. Lancet. Mar 22 2003;361(9362):1025-34
  4. Fotedar R, Stark D, Beebe N, et al. Laboratory diagnostic techniques for Entamoeba species. Clin Microbiol Rev. Jul 2007;20(3):511-32 Full Text