Difference between revisions of "Echovirus"

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(Created page with '{{PSDS|Animals and human |Direct contact, fecal-oral transmission, and occasionally waterborne transmission|Over 300 adenovirus infections in immunocompromised patients, with an …')
 
(Recommended Dose Response Model)
 
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{{PSDS|Animals and human |Direct contact, fecal-oral transmission, and occasionally waterborne transmission|Over 300 adenovirus infections in immunocompromised patients, with an overall case fatality rate of 48% (Hierholzer JC, 1992)<br /> A total of 428 respiratory HAdV infections were studied from 1991 to 2007 in Korean children and the case fatality ratio was 5.1% (Lee et al, 2010)|Adenoviruses C in non-hospitalized Mexican children older than five years of age showed a rate of AdV infection of 23% (Rosete et al, 2008) |3-10 days |Medium-sized (90-100 nm), nonenveloped icosohedral viruses containing double-stranded DNA |Unusually stable to chemical and physical agents and to adverse pH conditions| [[Dose response models for Adenovirus]] }}
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=Hosts=
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Human
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=Transmission/Exposure Routes=
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Person-to-person; the fecal-oral route is the predominant mode, although transmission sometimes occurs via respiration of oral secretions such as saliva. Indirect transmission occurs through numerous routes, including via contaminated water, food, and fomites (inanimate objects). Contaminated swimming and wading pools can also transmit the virus.<ref name=Wikipedia>http://en.wikipedia.org/wiki/Echovirus</ref>
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=Case Fatality Ratio=
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Deaths and other adverse consequences are rare and limited to patients with severe echovirus encephalitis or to persons with B cell-deficiency syndromes who develop persistent infection.<ref name=Modlin>Modlin, J. F. (1986). "[http://www.jstor.org/stable/4453981 Perinatal Echovirus Infection: Insights from a Literature Review of 61 Cases of SeriousInfection and 16 Outbreaks in Nurseries]." Reviews of Infectious Diseases '''8'''(6): 918-926.</ref><br /> Mortality was higher in infants with severe hepatitis (83%) than in infants with infection of the central nervous system (19%).<ref name=Modlin></ref>
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=Incubation Times=
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2 days and 2 weeks<ref name=Medscape>[http://emedicine.medscape.com/article/963458-overview#showall Medscape]</ref>
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=Burden of Disease=
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====Duration of infectiousness and disease====
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====Symptomology====
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====Latency====
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====Asymptomatic Rates====
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====Excretion Rates (see Exposure) ====
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====Immunity====
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=Microbiology=
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A type of RNA virus that belongs to the genus ''Enterovirus'' of the ''Picornaviridae'' family
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=Environmental Survival=
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Unusually stable to chemical and physical agents and to adverse pH conditions
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=Recommended Dose Response Model=
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[[Echovirus: Dose Response Models]] <br /> Beta-Poisson, α is 1.06, N<sub>50</sub> is 921.94 <br /> [[File:Betapoisson_model.jpg|thumb|left|300px]]
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<headertabs />
  
 
===References===
 
===References===
[http://www.cdc.gov/ncidod/dvrd/revb/respiratory/eadfeat.htm CDC Adenovirus Page] <br />
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<references/>
Hierholzer J. (1992) Adenoviruses in the Immunocompromised Host. Clinical Microbiology Reviews. 5(3): 262-274. [http://cmr.asm.org/cgi/reprint/5/3/262 Full Text] <br />
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Lee J, Choi E, and Lee H. (2010) Clinical severity of respiratory adenoviral infection by serotypes in Korean children over 17 consecutive years (1991-2007). Journal of Clinical Viroloty. 49: 115-120. [http://www.sciencedirect.com.proxy2.cl.msu.edu/science/article/pii/S138665321000274X Full Text] <br />
 
Rosete D, Manjarrez M, and Barron B. (2008) Adenoviruses C in non-hospitalized Mexican children older than five years of age with acute respiratory infection. 103(2): 195-200. [http://www-ncbi-nlm-nih-gov.proxy2.cl.msu.edu/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=18425273&dopt=abstractplus Abstract] <br />
 
  
  
[[Category:PSDS]]
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[[Category:Agent Overview]][[Category:Virus]]

Latest revision as of 13:42, 25 September 2012

[edit]

Human

Person-to-person; the fecal-oral route is the predominant mode, although transmission sometimes occurs via respiration of oral secretions such as saliva. Indirect transmission occurs through numerous routes, including via contaminated water, food, and fomites (inanimate objects). Contaminated swimming and wading pools can also transmit the virus.[1]

Deaths and other adverse consequences are rare and limited to patients with severe echovirus encephalitis or to persons with B cell-deficiency syndromes who develop persistent infection.[2]
Mortality was higher in infants with severe hepatitis (83%) than in infants with infection of the central nervous system (19%).[2]

2 days and 2 weeks[3]

Duration of infectiousness and disease

Symptomology

Latency

Asymptomatic Rates

Excretion Rates (see Exposure)

Immunity

A type of RNA virus that belongs to the genus Enterovirus of the Picornaviridae family

Unusually stable to chemical and physical agents and to adverse pH conditions

References

  1. http://en.wikipedia.org/wiki/Echovirus
  2. 2.0 2.1 Modlin, J. F. (1986). "Perinatal Echovirus Infection: Insights from a Literature Review of 61 Cases of SeriousInfection and 16 Outbreaks in Nurseries." Reviews of Infectious Diseases 8(6): 918-926.
  3. Medscape