Difference between revisions of "Campylobacter jejuni"

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==''Campylobacter jejuni''==
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=Host=
 
 
===Host===
 
 
Animals and humans
 
Animals and humans
  
===Transmission/Exposure Routes===
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=Transmission/Exposure Routes=
 
Fecal-oral, ingestion of contaminated food or water, and the eating of raw meat
 
Fecal-oral, ingestion of contaminated food or water, and the eating of raw meat
  
===Case Fatality Ratio===
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=Case Fatality Ratio=
 
Does not commonly cause death, it has been estimated that approximately 124 persons with Campylobacter infections die each year.
 
Does not commonly cause death, it has been estimated that approximately 124 persons with Campylobacter infections die each year.
 
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===Incubation Period===
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=Incubation Period=
 
3-5 days or up to a week <ref name=Medscape>[http://emedicine.medscape.com/article/213720-overview#showall Medscape Page]</ref>
 
3-5 days or up to a week <ref name=Medscape>[http://emedicine.medscape.com/article/213720-overview#showall Medscape Page]</ref>
  
===Burden of Disease===
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=Burden of Disease=
 
It is estimated to affect over 2.4 million persons every year, or 0.8% of the population. <ref name=CDC>[http://www.cdc.gov/nczved/divisions/dfbmd/diseases/campylobacter/ CDC Page]</ref> <br />
 
It is estimated to affect over 2.4 million persons every year, or 0.8% of the population. <ref name=CDC>[http://www.cdc.gov/nczved/divisions/dfbmd/diseases/campylobacter/ CDC Page]</ref> <br />
 
In 2010, the CDC reported an incidence 13.6 per 100,000 for Campylobacteriosis. <ref name=MMWR2010>Vital Signs: Incidence and Trends of Infection with Pathogens Transmitted Commonly Through Food --- Foodborne Diseases Active Surveillance Network, 10 U.S. Sites, 1996--2010. (n.d.). http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6022a5.htm?s_cid=mm6022a5_w</ref>
 
In 2010, the CDC reported an incidence 13.6 per 100,000 for Campylobacteriosis. <ref name=MMWR2010>Vital Signs: Incidence and Trends of Infection with Pathogens Transmitted Commonly Through Food --- Foodborne Diseases Active Surveillance Network, 10 U.S. Sites, 1996--2010. (n.d.). http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6022a5.htm?s_cid=mm6022a5_w</ref>
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====Immunity====
 
====Immunity====
  
===Microbiology===
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=Microbiology=
 
Gram-negative, spiral, and microaerophilic. Motile, with either unipolar or bipolar flagella, the organisms have a characteristic spiral/corkscrew appearance and are oxidase-positive
 
Gram-negative, spiral, and microaerophilic. Motile, with either unipolar or bipolar flagella, the organisms have a characteristic spiral/corkscrew appearance and are oxidase-positive
  
===Environmental Survival===
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=Environmental Survival=
 
<br />
 
<br />
  
===Recommended Dose Response Model===
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=Recommended Dose Response Model=
 
[[has DR model::Dose response models for Campylobacter]] <br /> Beta-Poisson, α is 0.14, N<sub>50</sub> is 890.38  
 
[[has DR model::Dose response models for Campylobacter]] <br /> Beta-Poisson, α is 0.14, N<sub>50</sub> is 890.38  
 
[[File:Betapoisson_model.jpg|thumb|left|300px]]
 
[[File:Betapoisson_model.jpg|thumb|left|300px]]
  
  
 
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<headertabs />
 
 
 
 
 
 
 
 
  
 
===References===
 
===References===
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<references/>
 
<references/>
 
<br>
 
<br>
[[Category:PSDS]][[Category:Bacterium]]
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[[Category:Agent Overview]][[Category:Bacterium]]

Revision as of 11:47, 3 August 2012

[edit]

Animals and humans

Fecal-oral, ingestion of contaminated food or water, and the eating of raw meat

Does not commonly cause death, it has been estimated that approximately 124 persons with Campylobacter infections die each year.

Case Fatality Ratio
Case Fatality Ratio Pathway/conditions Population References
0.19% (95% CI: 0.13-0.27%) Infected domestically (in Sweden)

Within first month following illness

Sweden [1]
0.008 (95% CI: 0.0008-0.03%) Infected Abroad (outside of Sweden)

Within first month following illness

Not Reported [1]
0.23% foodborne infection Denmark [2]

3-5 days or up to a week [3]

It is estimated to affect over 2.4 million persons every year, or 0.8% of the population. [4]
In 2010, the CDC reported an incidence 13.6 per 100,000 for Campylobacteriosis. [5]

Duration of infectiousness and disease

Symptoms typically reside in one week. Antibiotic treatment has been shown to decrease the duration of intestinal symptoms by 1.32 Days (95% CI: 0.64-1.99) However, because of drug resistance problems, antibiotics are only advised in complicated cases.[6]

Symptomology

Illness can cause symptoms beginning 2-5 days after exposures. These symptoms include abdominal pain, cramping, diarrhea, and fever.

Post-infectious complications include...

  • Reactive Arthritis (7%)
  • Guillain-Barre syndrome (1-3/10,000)
  • Bacteremia (<1%)

Feodoroff B.

Excretion Rates (see Exposure)

Immunity

Gram-negative, spiral, and microaerophilic. Motile, with either unipolar or bipolar flagella, the organisms have a characteristic spiral/corkscrew appearance and are oxidase-positive


References

Campylobacter Wiki Page

  1. 1.0 1.1 Ternhag, A., Törner, A., Svensson, Å., Giesecke, J., & Ekdahl, K. (2005). Mortality following Campylobacter infection: a registry-based linkage study. BMC Infectious Diseases, 5, 70. doi:10.1186/1471-2334-5-70 Full Text
  2. Helms, M., Vastrup, P., Gerner-Smidt, P., & Mølbak, K. (2003). Short and long term mortality associated with foodborne bacterial gastrointestinal infections: registry based study. BMJ : British Medical Journal, 326(7385), 357. Full Text
  3. Medscape Page
  4. CDC Page
  5. Vital Signs: Incidence and Trends of Infection with Pathogens Transmitted Commonly Through Food --- Foodborne Diseases Active Surveillance Network, 10 U.S. Sites, 1996--2010. (n.d.). http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6022a5.htm?s_cid=mm6022a5_w
  6. Ternhag, A., Asikainen, T., Giesecke, J., & Ekdahl, K. (2007). A Meta-Analysis on the Effects of Antibiotic Treatment on Duration of Symptoms Caused by Infection with Campylobacter Species. Clinical Infectious Diseases, 44(5), 696–700. doi:10.1086/509924 Full Text