Difference between revisions of "Campylobacter jejuni"
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Revision as of 15:15, 24 May 2012
Contents
Campylobacter jejuni
Host
Animals and humans
Transmission/Exposure Routes
Fecal-oral, ingestion of contaminated food or water, and the eating of raw meat
Case Fatality Ratio
Does not commonly cause death, it has been estimated that approximately 124 persons with Campylobacter infections die each year.
Case Fatality Ratio | Pathway/conditions | Population | References |
0.19% (95% CI: 0.13-0.27%) | Infected domestically (in Sweden)
Within first month following illness |
Sweden | [1] |
0.008 (95% CI: 0.0008-0.03%) | Infected Abroad (outside of Sweden)
Within first month following illness |
Not Reported | [2] |
0.23% | foodborne infection | Denmark | [3] |
Incubation Period
3-5 days or up to a week (Medscape)
Burden of Disease
It is estimated to affect over 2.4 million persons every year, or 0.8% of the population (CDC).
In 2010, the CDC reported an incidence 13.6 per 100,000 for Campylobacteriosis. [4]
Duration of infectiousness and disease
Symptoms typically reside in one week. Antibiotic treatment has been shown to decrease the duration of intestinal symptoms by 1.32 Days (95% CI: 0.64-1.99) However, because of drug resistance problems, antibiotics are only advised in complicated cases.[5]
Symptomology
Illness can cause symptoms beginning 2-5 days after exposures. These symptoms include abdominal pain, cramping, diarrhea, and fever.
Excretion Rates (see Exposure)
Immunity
Microbiology
Gram-negative, spiral, and microaerophilic. Motile, with either unipolar or bipolar flagella, the organisms have a characteristic spiral/corkscrew appearance and are oxidase-positive
Environmental Survival
Recommended Dose Response Model
Dose response models for Campylobacter
Beta-Poisson, α is 0.14, N50 is 890.38
References
CDC Campylobacter Page
Campylobacter Wiki Page
Campylobacter Medscape Page
- ↑ Ternhag, A., Törner, A., Svensson, Å., Giesecke, J., & Ekdahl, K. (2005). Mortality following Campylobacter infection: a registry-based linkage study. BMC Infectious Diseases, 5, 70. doi:10.1186/1471-2334-5-70 Full Text
- ↑ Cite error: Invalid
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- ↑ Helms, M., Vastrup, P., Gerner-Smidt, P., & Mølbak, K. (2003). Short and long term mortality associated with foodborne bacterial gastrointestinal infections: registry based study. BMJ : British Medical Journal, 326(7385), 357. Full Text
- ↑ Vital Signs: Incidence and Trends of Infection with Pathogens Transmitted Commonly Through Food --- Foodborne Diseases Active Surveillance Network, 10 U.S. Sites, 1996--2010. (n.d.). Retrieved May 24, 2012, from http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6022a5.htm?s_cid=mm6022a5_w
- ↑ Ternhag, A., Asikainen, T., Giesecke, J., & Ekdahl, K. (2007). A Meta-Analysis on the Effects of Antibiotic Treatment on Duration of Symptoms Caused by Infection with Campylobacter Species. Clinical Infectious Diseases, 44(5), 696–700. doi:10.1086/509924 Full Text