Yersinia pestis

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• Hosts
• Transmission/Exposure Routes
• Incubation Times
• Case Fatality Ratios
• Burden of Disease
• Microbiology
• Environmental Survival
• Recommended Dose Response Model

Human and animals

Transmitted to humans from infected flees and rodents are reservoirs of the disease (dose response page for Yersinia pestis)

2–6 days for Bubonic plague

Case Fatality Ratios

Disease	Untreated	Treated	Reference
Pneumonic plague	100%	50%
Bubonic plague	50%-90%	10%-20%
Septicemic plague	20%-25%

The CDC has reported an average of 10-15 cases of yersinia pestis infection annually in the United States. Areas of natural occurrence of plague in the United States include Arizona, California, Colorado, New Mexico, and Utah. Internationally between 1990-1995, a total of 12,998 cases of plague were reported to the World Health Organization (WHO), mostly from countries such as India, Zaire, Peru, Malawi, and Mozambique.

Duration of Infectiousness and disease

Symptomology

Latency

Asymptomatic Rates

Excretion Rates (see Exposure)

Immunity

A Gram-negative facultative anaerobic bipolar-staining bacillus bacterium belonging to the family Enterobacteriaceae

Yersinia pestis: Dose Response Models
Exponential, k is 1.63E-03

References

http://www.cdc.gov/pulsenet/pathogens_pages/yersinia.htm