Shigella sp.
- Hosts
- Transmission/Exposure Routes
- Incubation Times
- Case Fatality Ratios
- Burden of Disease
- Microbiology
- Environmental Survival
- Recommended Dose Response Model
Humans
Incubation period of the disease is 1-4 days which is usually followed by sudden onset of acute symptoms.[1]
The overall mortality rate in developed countries is less than 1%. In the Far East and Middle East, the mortality rates for S dysenteriae infections may be as high as 20-25%.(Medscape)
Location | Mortality Rate | Reference |
Developed Countries | <1% | (Medscape) |
Far East/Middle East | 20-25% | (Medscape) |
The incidence of Shigella infections was 2848 cases per 100,000 population in 2007 (Medscape)
Duration of Infectiousness and disease
Symptomology
Range from mild diarrhea to severe dysentery with frequent passage of bloody, mucoid, small-volume stools. May cause destruction of colon epithelium resulting in acute colitis. [2]
Latency
Asymptomatic Rates
Excretion Rates (see Exposure)
An infected person excretes the organisms in the stool and this can extend up to 4 weeks from the onset of illness.[1]
Immunity
Currently, no vaccine exists to prevent Shigellosis. However, individuals who have already been infected are generally immune to further infection by the same species. [3] Broad spectrum antibiotic resistance is becoming increasingly prevalent, especially in antimicrobial drug sulfonamides, decycline, chloramphenicol, and ampicillin. [4]
A genus of Gram-negative, nonspore forming, non-motile, rod-shaped bacteria (Wikipedia)
References
Wikipedia Page
Medscape Page
CDC Shigellosis Page
Recent Works on Microbes and Infections in China
- ↑ 1.0 1.1 1.2 1.3 Sur, Dipika et al. “Shigellosis : Challenges & Management Issues.” The Indian Journal of Medical Research 120.5 (2004): 454–462.
- ↑ http://site.ebrary.com.proxy1.cl.msu.edu/lib/michstate/docDetail.action?docID=10422483>
- ↑ CDC http://www.cdc.gov/nczved/divisions/dfbmd/diseases/shigellosis/#diagnose>
- ↑ http://site.ebrary.com.proxy1.cl.msu.edu/lib/michstate/docDetail.action?docID=10422483>