Feeding Experiment for Coxiella burnetii

Experiment data

Experiment 1. Mice/phase I Ohio strain interperitoneal data Dose(PFU) Dead Survived Total 7.00E+10 19 1 20 7.00E+09 23 7 30 7.00E+08 16 14 30 7.00E+07 6 24 30 7.00E+06 1 19 20 7.00E+05 0 30 30 7.00E+03 0 30 30 7.00E+01 0 30 30 7.00E+00 0 20 20 7.00E-01 0 30 30 Williams et al., 1982.

Experiment 2. Mice/Nine mile phase I strain interperitoneal data Dose(PFU) Dead Survived Total 5.01E+10 9 1 10 5.01E+09 3 7 10 5.01E+08 1 9 10 5.01E+07 0 10 10 5.01E+06 0 10 10 5.01E+05 0 10 10 5.01E+04 0 10 10 5.01E+03 0 10 10 5.01E+02 0 10 10 5.00E+01 0 10 10 5.00E+00 0 10 10 5.00E-01 0 10 10 5.00E-02 0 10 10 Scott et al., 1987.

References

Williams, J. C. and J. L. Cantrell (1982). "Biological and immunological properties of Coxiella burnetii vaccines in C57BL/1OScN endotoxin-nonresponder mice." Infection and Immunity 35(3): 1091–1102.

Scott, G. and J. C. Williams (1987). "Pathological responses of inbred mice to phase I Coxiella Burnetii." Journal of General Microbiology 133(3): 691–700.