- Transmission/Exposure Routes
- Case Fatality Ratio
- Incubation Period
- Burden of Disease
- Envrionmental Survival
- Recommended Dose Response Model
Animals and human
Either through the cutaneous or inhalation. Person-to-person transmission is exceedingly unusual.
|Case Fatality Ratio||Pathway/conditions||Population||References|
|33.8% (of 145)||Not Reported|| Alor Setar region of Kedah, Malaysia
Mean age of 50 years
|10%||Uncomplicated cases||Not Reported|||
|up to 80%||Cases with bacteraemia or sepsis||Not Reported|||
|41% (11/27)||28-day mortality rate||Not Reported|||
|36.9% (79/214)||Not Reported||Adult Thai Patients|||
|36% (12/33)||With therapy and intensive care||Northern Australia (1990-91 outbreak)|||
|1-21 days (mean: 9)||Cutaneous/Inhalation||Norhtern Australia 1989-99 (252 cases)|||
|16.35 per 100,000||Alor Setar region, Kedah, Malaysia|||
|4.9 per 100,000 (95% CI: 3.9-6.1)||Sa Kaeo, Thailand 2006-08|||
|14.9 per 100,000(95% CI: 13.3-16.6)||Nakhon Phanom, Thailand 2006-08|||
Duration of infectiousness and disease
In the 10 year study (1989-99) completed in Northern Australia, 252 cases of Melioidosis were examined for acute and chronic illness and also relapse and reactivation.
Acute illness (<2 months) occurred in 222 (88%) of the cases.
Chronic illness (symptomatic for >2 months) occurred in 30 (12%) of the cases.
Of the survivors of the initial infection (207 patients), 27 (13%) had a confirmed relapse over 10 years.
Some recognizable symptoms of Melioidosis are common flu-like symptoms, such as cough, chest pain, high fever, headache, and loss of appetite. Other symptoms indicative of a bloodstream infection include respiratory distress, abdominal discomfort, joint pain, muscle tenderness, disorientation. Disseminated infection symptoms also are weight loss, stomache or chest pain, and possible seizures. A localized infection can produce localized pain and sweling with ulceration and abscess.
Excretion Rates (see Exposure)
Gram -, facultative anaerobic, motile bacillus 
Exponential model: optimal value of k is 1.0 E-04
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