Bacillus Anthracis: Feeding Experiments

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Experiment 1: Guinea pig/Vollum Strain Intranasal data
Dose(spores) Dead Survived Total
20,000,000 7 0 7
2,000,000 7 1 8
200,000 10 2 12
20,000 6 6 12
2,000 0 8 8
200 0 4 4
Altboum et al., (2002)
Experiment 2: Guinea pig/ATCC 6605 Strain Intranasal data
Dose(spores) Dead Survived Total
3,000,000 10 0 10
300,000 8 2 10
30,000 3 7 10
3,000 0 10 10
300 1 5 6
30 0 6 6
Altboum et al., (2002)
Experiment 3: Rhesus Macaques/Vollum Strain Inhalation data
Dose(spores) Dead Survived Total
70320 1 7 8
77040 4 4 8
108720 5 3 8
137520 6 2 8
155520 5 3 8
160800 3 5 8
240000 8 0 8
300000 7 1 8
398400 8 0 8
Druett et al., (1953)
Experiment 4: Guinea pig/Vollum Strain Inhalation data
Dose(spores) Dead Survived Total
19820 8 24 32
40828 16 14 30
76230 21 11 32
118000 28 4 32
Druett et al., (1953)

References

Altboum Z., Gozes, Y., Barnea, A., Pass, A., White, M., Kobiler, D. (2002) Postexposure prophylaxis against anthrax: Evaluation of various treatment regimes in intranasally infected guinea pigs Infection and Immunity 70(1): 6231-6241
Full Text via PubMed

Druett, H.A., Henderson, D.W., Packman, L., Peacock, S. (1953) Studies on respiratory infection. I. The influence of particle size on respiratory infection with anthrax spores Journal of Hygiene 51: 359-371
Full Text PDF via NIH