Adenovirus

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Animals and humans [1]

Direct contact, fecal-oral transmission, and occasionally waterborne transmission [1]

Case fatality ratios
Case Fatality Ratio Pathway/conditions Population References
48%(of over 300) Immunocompromised [2]
5.1%(of 428) 1991-2007 Korean Children [3]

3-10 days

Adenoviruses C in non-hospitalized Mexican children older than five years of age showed a rate of AdV infection of 23%. [4]

Duration of infectiousness and disease

Symptomology

Symptoms include colds, sore throat, bronchitis, pneumonia, diarrhea, pink eye, fever, bladder inflammation or infection, inflammation of stomach and and intestines, and neurologic disease. These symptoms can vary depending on how a person becomes infected. For example, breathing in adenovirus may be more likely to cause respiratory illnesses. [5]

Excretion Rates (see Exposure)

Adenovirus can persist in the tonsils, adenoids, and intestines for months or years. This is a persistent adenovirus infection which usually shows no symptoms. [5]

Immunity

Currently there is no vaccine available to the general public. However, military personnel can obtain a vaccine for adenovirus types 4 and 7. [5]

Medium-sized (90-100 nm), nonenveloped icosohedral viruses containing double-stranded DNA [5]

Unusually stable to chemical and physical agents and to adverse pH conditions [1]

References

  1. 1.0 1.1 1.2 Wiki
  2. Hierholzer J. (1992) Adenoviruses in the Immunocompromised Host. Clinical Microbiology Reviews. 5(3): 262-274. Full Text
  3. Lee J, Choi E, and Lee H. (2010) Clinical severity of respiratory adenoviral infection by serotypes in Korean children over 17 consecutive years (1991-2007). Journal of Clinical Virology. 49: 115-120. Full Text
  4. Rosete D, Manjarrez M, and Barron B. (2008) Adenoviruses C in non-hospitalized Mexican children older than five years of age with acute respiratory infection. 103(2): 195-200. Abstract
  5. 5.0 5.1 5.2 5.3 CDC http://www.cdc.gov/adenovirus/index.html Cite error: Invalid <ref> tag; name "CDC" defined multiple times with different content